产品货号:
Z12049
中文名称:
BRSK2抗体
英文名称:
Anti-BRSK2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-BRSK2 Antibody |
指标别名 | BR serine/threonine kinase 2;BRSK2;C11orf7;PEN11B;SAD1;STK29 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | BRSK2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | BRSK2 antibody was raised against a 23 amino acid synthetic peptide from near the carboxy terminus of human BRSK2.The immunogen is located within amino acids 630 - 680 of BRSK2. |
计算分子量 | 82kDa |
成分 | BRSK2 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | BRSK2 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | BRSK2 was initially identified through a computer screen of the human genome and shows significant homology to the C.elegans neuronal cell polarity regulator SAD1.BRSK2 is expressed in the brain and to a lesser extent in the testes.BRSK2 is a member of the AMP-activated protein kinase subfamily and can be activated by the tumor suppressor kinase LKB1.More recently,it has been shown that both BRSK2 and the related protein BRSK1 are required for mammalian neuronal polarization.While BRSK1- and BRSK2-null mice were viable,double-mutant mice died within two hours of birth.Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites.These neurites also displayed both axonal and dendritic markers.BRSK2 has also been shown to be an autoantigen in paraneoplastic limbic encephalitis.At least four isoforms of BRSK2 are known to exist. |
Uniprot ID | Q8IWQ3 |
基因名全称 | BR serine/threonine kinase 2 |
蛋白名全称 | BR serine/threonine kinase 2 |
推荐稀释比 | BRSK2 antibody can be used for detection of BRSK2 by Western blot at 0.5 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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